Roger J Davey

Special Issue Published as part of Crystal Growth & Design special issue “Design of Crystals via Crystallization Processes.” 1. Introduction Click to copy section linkSection link copied! Impurities are very difficult to avoid during crystal growth; they are often found in starting materials, as byproducts, or unreacted species present in the crystallization environment.

Symthons reveal how fluorine disrupts π–π stacking in halobenzene crystal structures† Symmetry-forming closest approaches of aromatic rings; ‘Symthons’, are usually the strongest interactions in halobenzene crystal structures. Where they combine to create π–π stacking, they are as strong as hydrogen bonds. This π–π stacking is disrupted when fluorine is present, as revealed in this analysis of all 290 closest aromatic approaches in the crystal structures of halobenzenes.

Do metastable polymorphs always grow faster? Measuring and comparing growth kinetics of three polymorphs of tolfenamic acid The phenomenon of molecular crystal polymorphism is of central importance for all those industries that rely on crystallisation for the manufacturing of their products. Computational methods for the evaluation of thermodynamic properties of polymorphs have become incredibly accurate and a priori prediction of crystal structures is becoming routine.