April 18, 2026, 5:01 a.m. MT Route 66, known as the "Main Street of America," will celebrate its 100th anniversary on Nov. 11, 2026. After being decommissioned in 1985, the highway was revived thanks to efforts started by Seligman barber Angel Delgadillo. Arizona was the first state to designate a portion of the road as "Historic Route 66" in 1987, creating a model for other states.