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LHCGR Inactivating Variants: Single Center Experience and Systematic Review of Phenotype-Genotype of 46, XY and 46, XX Patients
Faculty, Staff and Student Publications Publication Date 10-1-2024 Journal Endocrine Connections PubMedCentral® Posted Date 10-4-2024 PubMedCentral® Full Text Version Post-print Abstract Background: The data on Leydig cell hypoplasia (LCH) resulting from biallelic Luteinizing hormone/chorionic gonadotropin receptor (LHCGR) inactivating variants is limited to case series.
Diagnostic Accuracy of Serum Steroids and Peptides in the Evaluation of 46, XY Disorders of Sex Development (DSD)
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description cen70017-sup-0001-1_3_25_Supplementary_Data.docx68.4 KB Supplementary Table 1: Genotypic Characteristics of Patients with 46, XY Disorders of Sex Development (DSD). Supplementary Table 2: Serum biochemistry in Differences of Sex Differentiation (DSD). Supplementary Table 3: Utility of serum T/DHT ratio for SRD5A2 deficiency diagnosis.
Prevalence of Primary Aldosteronism in T2D and Hypertension
Abstract and Introduction Abstract Objective: Type 2 diabetes mellitus (T2DM) and hypertension commonly coexist; however, underlying primary aldosteronism (PA) can lead to worsening of hypertension, glycemia and cardiovascular risk. We aim to screen patients with T2DM and hypertension for PA by conducting a prospective monocentric study from Western India, which included adults with T2DM and hypertension from the outpatient diabetes clinic. Design: Prospective study.
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