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Rohita Roy

As seen in: BioRxiv
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Articles

Design of a Modular Inducible Circuit for Pulsatile Population Control of Engineered Bacteria

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By Michaëlle N. Mayalu, Rohita Roy
| BioRxiv
Abstract Synthetic biology enables the precise control of bacterial population dynamics through engineered genetic circuits, paving the way for innovative therapeutic and biosensing applications. Here, we present genetic circuit design that leverages AHL (acyl-homoserine lactone)-based quorum sensing and a transcriptional cascade regulated by an external inducer to drive synchronized proliferation and lysis events.
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