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Roland B. Liu

As seen in: Science Magazine, BioRxiv
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Articles

A simple solid media assay for detection of synergy between bacteriophages and antibiotics

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By Joseph Oh, Roland B. Liu, Ethan Khong, Julian M Jiminez
| BioRxiv
Abstract The emergence of antibiotic resistant bacteria (ARB) has necessitated the development of alternative therapies to deal with this global threat. Bacteriophages (viruses that target bacteria) that kill ARB are one such alternative. While phages have been used clinically for decades with inconsistent results, a number of recent advances in phage selection, propagation and purification have enabled a reevaluation of their utility in contemporary clinical medicine.
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Fecal virome transplantation is sufficient to alter fecal microbiota and drive lean and obese body phenotypes in mice

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By Joshua M. Borin, Roland B. Liu, Yanhan Wang, Tsung-Chin Wu
| BioRxiv
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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Metabolic differentiation and intercellular nurturing underpin bacterial endospore formation

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By Javier Lopez-Garrido, Joseph Sugie, Eammon P. Riley, Roland B. Liu
| Science Magazine Verified
Abstract Despite intensive research, the role of metabolism in bacterial sporulation remains poorly understood. Here, we demonstrate that Bacillus subtilis sporulation entails a marked metabolic differentiation of the two cells comprising the sporangium: the forespore, which becomes the dormant spore, and the mother cell, which dies as sporulation completes.
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