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Neuropilin-1 Is Expressed on Highly Activated CD4+ Effector T Cells and Dysfunctional CD4+ Conventional T Cells from Naive Mice
Hanna Abberger, Romy Barthel, Jasmin Bahr, Jacqueline Thiel, Sina Luppus, Jan Buer, Astrid M. Westendorf and Wiebke Hansen J Immunol September 1, 2021, 207 (5) 1288-1297; DOI: https://doi.org/10.4049/jimmunol.2100222 Key Points Nrp-1 expression is induced on a subset of CD4+Foxp3− T cells upon stimulation. Stimulation-induced iNrp-1+CD4+Foxp3− T cells exhibit a highly activated phenotype. Pre-existing nNrp-1+CD4+Foxp3− T cells from naive mice are dysfunctional.
Neuropilin-1 Is Expressed on Highly Activated CD4+ Effector T Cells and Dysfunctional CD4+ Conventional T Cells from Naive Mice
Hanna Abberger, Romy Barthel, Jasmin Bahr, Jacqueline Thiel, Sina Luppus, Jan Buer, Astrid M. Westendorf and Wiebke Hansen J Immunol August 2, 2021, ji2100222; DOI: https://doi.org/10.4049/jimmunol.2100222 Key Points Nrp-1 expression is induced on a subset of CD4+Foxp3− T cells upon stimulation. Stimulation-induced iNrp-1+CD4+Foxp3− T cells exhibit a highly activated phenotype. Pre-existing nNrp-1+CD4+Foxp3− T cells from naive mice are dysfunctional.
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