Romy Böhme on Muck Rack

Romy Böhme

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Articles

Cardiovascular changes in the NZB/W F1 mouse model of lupus nephritis

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By Ming-Lin Liu, Yudong Liu, Romy Böhme
| Frontiers
1. Introduction Systemic lupus erythematosus (SLE) is an autoimmune disease that results in inflammatory reactions in various tissues, such as the kidney, skin, heart, and nervous system, followed by severe organ damage, i.e., heart failure or end-stage renal disease (ESRD) (1, 2). SLE is characterized by the development of auto-antibodies, such as antibodies to double-stranded (ds) DNA, and activation of the complement system, leading to inflammatory cell infiltration and organ damage (3).
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