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ABSTRACT Background Point-of-care testing (POCT) can reduce diagnostic gaps, but because it frequently falls to overstretched frontline healthcare workers (HCW), its real-world effectiveness is diminished. Despite World Health Organization recommendations for task sharing (TS) with lay health workers (LHW), it remains underutilized. Objective To explore whether task-shifted POCT by LHWs can improve uptake compared to standard HCW-led care.
You are already at the latest version Introduction: Noma is a severe gangrenous orofacial disease affecting malnourished children aged 2–6 years in extreme poverty, with 85–90% mortality if untreated. Recently classified as a Neglected Tropical Disease, it is managed mainly with empirical broad-spectrum antibiotics. Antimicrobial resistance (AMR) threatens to undermine treatment, yet AMR remains largely absent from Noma research and policy.
This case report presents a 23-year-old Congolese female patient with HIV on first line antiretroviral drugs (tenofovir–lamivudine–dolutegravir) since November 2019 following HIV diagnosis in a tertiary center. Underlying conditions included tuberculosis (TB) meningitis, which was under treatment since February 2021. The patient trajectory is outlined in Fig. 1. Patient timeline prior to hospitalization in November 2021 The patient history revealed that initial symptoms were dominated by headaches.
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