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Abstract HIV-associated neurocognitive impairment (HIV-NCI) affects 15%–50% of people with HIV (PWH), despite viral suppression with antiretroviral therapy (ART). HIV neuropathogenesis is mediated, in part, by transmigration of infected CD14+CD16+ monocytes across the blood-brain barrier (BBB) into the central nervous system (CNS).
Research Article | Host-Microbe Biology Rosiris León-Rivera, Brenda Morsey, Meng Niu, Howard S. Fox, Joan W. Berman Bruce D. Walker, Invited Editor, Stephen P. Goff, Editor DOI: 10.1128/mBio.01037-20 ABSTRACT HIV reservoirs persist despite successful antiretroviral therapy (ART) and are a major obstacle to the eradication and cure of HIV. The mature monocyte subset, CD14+CD16+, contributes to viral reservoirs and HIV-associated comorbidities.
Correction: Macrophage Mitochondrial and Stress Response to Ingestion of Cryptococcus neoformans Carolina Coelho, Ana Camila Oliveira Souza, Lorena da Silveira Derengowski, Carlos de Leon-Rodriguez, Bo Wang, Rosiris Leon-Rivera, Anamelia Lorenzetti Bocca, Teresa Gonçalves, Arturo Casadevall The Journal of Immunology September 1, 2017, 199 (5) 1944; DOI: 10.4049/jimmunol.1700948
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