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Rouya El Dani on Muck Rack

Rouya El Dani

As seen in: Nature
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Articles

Variable performance of HSV-2 IgG assays highlights the importance of western blot confirmation in a low-prevalence population

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By Nouran Zein, Farah Trad, Farah Ahmed Issa, Parveen B. Nizamuddin, Marah Abdallah, Houssein Ayoub, Atiyeh M Abdallah, Hisham ElBanawy, Laith J. AbuRaddad, Gheyath K. Nasrallah, Rouya El Dani
| Nature Verified
Abstract Herpes simplex virus type 2 (HSV-2) is a highly prevalent sexually transmitted infection, underscoring the importance of accurate serodiagnosis. While enzyme-linked immunosorbent assays (ELISAs) are commonly used clinically, their diagnostic performance compared to gold standard western blot (WB) remains uncertain. To compare the diagnostic accuracy of two ELISA-based assays, HerpeSelect 2 and NovaLisa, with the Euroimmun HSV-2 WB assay for the detection of HSV-2-specific IgG antibodies.
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