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Rovin N. Lachmansingh on Muck Rack

Rovin N. Lachmansingh

As seen in: Nature
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Regional diversity of cranial skeletal stem cells governs bone morphogenetic protein-2 mediated bone regeneration

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By Eri Takematsu, Kyle Johnston, Sophia Hou, Yuting Wang, Liming Zhao, Malachia Hoover, Hieu Nguyen, Hiếu Nguyễn, Heather E. Talbott, Michael T. Longaker, Charles Chan, Rovin N. Lachmansingh, Elyon Bailey, Kumarizeel M. Parmar
| Nature Verified
Abstract Skeletal stem cells (SSCs), originally identified in 2015, are increasingly understood to exhibit significant heterogeneity throughout the body. Cranial SSCs provide a unique model to investigate this diversity because cranial bones arise from both neural crest and mesoderm, unlike mesoderm-derived long bones. Here, we show that cranial SSCs possess anatomically defined transcriptomic and functional heterogeneity.
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