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Roya Chegene Lorestani on Muck Rack

Roya Chegene Lorestani

As seen in: Taylor & Francis Online
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Articles

Computational design of a fimbriae-derived multi-epitope vaccine candidate against Klebsiella pneumoniae

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By Farjam Goudarzi, Roya Chegene Lorestani, Tarek A. Ahmad, Hana Heidarinia
| Taylor & Francis Online
Abstract Klebsiella pneumoniae is a pathogen that causes infections in various parts of the body, with high mortality rates reported in antibiotic-resistant cases. Treating at-risk individuals requires crucial vaccination efforts due to the challenges that exist. This research involved designing a multi-epitope vaccine from K. pneumoniae’s fimbriae antigens. Optimal T-cell and B-cell epitopes were chosen through in silico studies including epitope-HLAs molecular docking.
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