Rozaimi Razali on Muck Rack

Rozaimi Razali

As seen in: Nature, MDPI, The Lancet
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Articles

The biomedical landscape of genomic structural variation in the qatari population - Nature Communications

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By Elbay Aliyev, Najeeb Syed, Aziz Belkadi, Haroon Naeem, Gaurav Thareja, Waleed Aamer, Farooq Omar Al-Ajli, Rozaimi Razali, Fritz J Sedlazeck, Younes Mokrab, Mario Falchi
| Nature Verified
Abstract We present a large-scale study of structural variation (SV) in the Qatari population, based on short-read whole-genome sequencing (WGS) of 6,141 individuals, identifying 153,946 variants across 5 classes reflecting the region’s diversity and evolutionary history. Leveraging consanguinity and biobank phenotypes, we identify >180 putative gene knockouts, and use proteomics to show functional consequences in homozygotes.
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Near-complete Middle Eastern genomes refine autozygosity and enhance disease-causing and population-specific variant discovery - Nature Genetics

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By Shabir Moosa, Radi Farhad, Francesco Kumara Mastrorosa, Katherine Munson, Rozaimi Razali, Elbay Aliyev, Rawan Abouelhassan, Lisa Mathew, Fazulur Rehaman Vempalli, Khalid A Fakhro, Arang Rhie, Evan E. Eichler
| Nature Verified
Abstract Advances in long-read sequencing have enabled routine complete assembly of human genomes, but much remains to be done to represent broader populations and show impact on disease-gene discovery. Here, we report highly accurate, near-complete and phased genomes from six Middle Eastern (ME) family trios (n = 18) with neurodevelopmental conditions, representing ancestries from Sudan, Jordan, Syria, Qatar and Afghanistan.
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Cancers | Free Full-Text | Genomic Alterations, Gene Expression Profiles and Functional Enrichment of Normal-Karyotype Acute Myeloid Leukaemia Based on Targeted Next-Generation Sequencing

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By Rozaimi Razali, Sarina Sulong, Angeli Ambayya, Ezzanie Suffya Zulkefli
| MDPI
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