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Articles by Ruby Tsang
Genetic and sociodemographic factors associated with trajectories of physical and mental health multimorbidity in a South Asian cohort in the UK: A multistate modelling analysis
Loading metrics Open Access Peer-reviewed Research Article Citation: Stow D, Tsang RSM, Katzourou IK, Huang Q, Samuel M, Wood ML, et al. (2026) Genetic and sociodemographic factors associated with trajectories of physical and mental health multimorbidity in a South Asian cohort in the UK: A multistate modelling analysis. PLoS Med 23(7): e1004844.
Recurrent Copy Number Variants and Psychiatric Outcomes in the Context of Polygenic Scores
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Recurrent Copy Number Variants and Psychiatric Outcomes in the Context of Polygenic Scores Supplement 1. eFigure 1. Associated Odds Ratios and Confidence Intervals Resulted From the Sensitivity Analysis for Grouping rCNVs Across 6 Different Approaches eFigure 2. Comparison of rCNV Group-Associated Absolute Risk Between SSD and SSD Without Comorbid Childhood-Onset Disorders in iPSYCH2015 eFigure 3.
By Morteza Vaez, Simone Montalbano, Ryan K. Waples, Morten Krebs, Kajsa-Lotta Georgii Hellberg, Jesper R. Gådin, Daniel Stow, Peter A Holmans, Anders D. Børglum, Dorte Helenius, Thomas Werge, Andrew J. Schork, Andrés Ingason, LINC Consortium, George G. Kirov, Michael Owen, James Walters, Jane Lynch, David van Heel, Sarah Finer, Nicholas J Timpson, John MacLeod Verified, Julie Clayton, Ruby Tsang, Jane Sprackman, Shahid Khan, Inês Barroso, Rupert A Payne, Mark A. Mon-Williams, Megan Wood, Nabila Ali, Hilary C. Martin, Lam O. Huang, Marianne van den Bree, Ioanna K. Katzourou, Golam M. Khandakar
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JAMA Psychiatry
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Patterns of inflammation in childhood and mental and cardiometabolic disorders in adulthood: mapping the trajectories
Mental and cardiometabolic disorders rank among the leading causes of burden of disease worldwide (Global Burden of Disease Collaborative Network, 2024). These disorders are highly multimorbid (i.e., the presence of 2 or more long-term conditions), and their relationship appears to be bidirectional (Nakada et al., 2023; Nuyen et al., 2021; Ronaldson et al., 2021).
Blood Immuno-metabolic Biomarker Signatures of Depression and Affective Symptoms in Young Adults
The authors have declared no competing interest. GMK acknowledges funding support from the UK Medical Research Council (MRC), grant no: MC_UU_00032/06, which forms part of the Integrative Epidemiology Unit at the University of Bristol. This grant also supports HF and EMF.
Adverse events after first and second doses of COVID-19 vaccination in England: a national vaccine surveillance platform self-controlled case series study - Ruby SM Tsang, Utkarsh Agrawal, Mark Joy, Rachel Byford, Chris Robertson, Sneha N Anand, William H
Introduction The coronavirus disease 2019 (COVID-19) immunisation programme in the United Kingdom (UK) began in December 2020, with the UK’s Joint Committee on Vaccination and Immunisation (JCVI) initially recommending COVID-19 vaccination for all adults aged 18 years and over, and prioritising older adults, care home residents and staff, health and social care workers, and individuals in clinical risk groups.
COVID-19 vaccine effectiveness against hospitalisation and death of people in clinical risk groups during the Delta variant period: English primary care network cohort study
Summary COVID-19 vaccines have been shown to be highly effective against hospitalisation and death following COVID-19 infection. COVID-19 vaccine effectiveness estimates against severe endpoints among individuals with clinical conditions that place them at increased risk of critical disease are limited. We used English primary care medical record data from the Oxford-Royal College of General Practitioners Research and Surveillance Centre sentinel network (N > 18 million).
Development of a modified Cambridge Multimorbidity Score for use with SNOMED CT: an observational English primary care sentinel network study
Data source and variables The study used pseudonymised CMR data from the RSC sentinel network database, which is recruited to be representative of the general population.12 The UK has registration-based primary care in which each patient registers with a single general practice. All patients who were registered for ≥12 months before the study index date (study start date) and aged ≥16 years at the study index date for each model were included.
Development of a modified Cambridge Multimorbidity Score for use with SNOMED CT: an observational English primary care sentinel network study
Data source and variables The study used pseudonymised CMR data from the RSC sentinel network database, which is recruited to be representative of the general population.12 The UK has registration-based primary care in which each patient registers with a single general practice. All patients who were registered for ≥12 months before the study index date (study start date) and aged ≥16 years at the study index date for each model were included.
Highlights • We present a serological survey of COVID-19 infections in England. • This study used sera collected alongside routine blood tests in primary care. • Seropositivity was higher in younger age and in Black and Asian ethnicities, • and also higher in major conurbations and in non-smokers. • We found no difference by deprivation, sex or shielding recommendation.
Pfizer-BioNTech and Oxford AstraZeneca COVID-19 vaccine effectiveness and immune response among individuals in clinical risk groups
Highlights • COVID-19 vaccine antibody response and effectiveness was evaluated among clinical risk groups. • High effectiveness was observed and normal response maintained in most risk groups.
Long covid: coding is caring
Intended for healthcare professionals Toggle navigation The BMJ logo Toggle top menu News & Views Long covid: coding is...
Coding is Caring
Dear Editor, Sivan et al’s editorial (1) and Ayoubkhani et al (2) helpfully describe the scale of adverse health outcomes for people hospitalised with COVID-19. We agree, that key questions are yet to be answered of this complex, heterogeneous patient group such as whether particular symptom clusters exist, the impact on disparities, and whether the young fit population are disproportionately affected (3).
G20團隊呈獻 ：連登眾籌熱烈祝賀中国70大壽！
【1255HKT Update】 大家好，我們知道有不少朋友見到我們「賀佢老母」的眾籌宣傳時會問，你們會否「玩膠」？我們可以非常肯定的告訴大家：我們絕不玩膠。 如果大家有留意我們先前兩次的登報（包括628 G20以及819），就會知道我們會認真地將我們希望國際社會關注的事項，包括香港人面臨的危機及國際社會上可行的支援行動確實描述。 選擇於國慶行動只是我們團隊在收集大家意見後，認為具有重大意義，可突顯中共在香港和世界的破壞，先前眾籌宣傳純屬綽頭，請大家放心並繼續多多支持，感謝大家的關心和意見。 【震驚七十億人！G20團隊呈獻：眾籌熱烈祝賀中国70大壽】 當今世界強國—中国即將迎接七十歲大壽，相信各位香港人也非常期待和興奮。 特首林鄭月娥宣布撤回《逃犯修訂條例草案》，妄圖使香港人讓步，放棄抗爭，不再堅持五大訴求。但當我們念及在太子站、新屋嶺等多地發生無法無天的警暴，眼見沒有民主的制度能如此快速地崩壞，我們香港人只會更加堅定地抗爭，絕不輕言放棄。...
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