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Michael Owen on Muck Rack

Michael Owen

Cardiff
As seen in: Daily Mail, Irish Daily Mail, Nature, Scottish Daily Mail, The Guardian, PLOS ONE, Journal of Homosexuality, MDPI, Genome Medicine, JAMA Psychiatry and
Professor of Psychological Medicine, Cardiff
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Articles

Recurrent Copy Number Variants and Psychiatric Outcomes in the Context of Polygenic Scores

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By Morteza Vaez, Simone Montalbano, Ryan K. Waples, Morten Krebs, Kajsa-Lotta Georgii Hellberg, Jesper R. Gådin, Daniel Stow, Peter A Holmans, Anders D. Børglum, Dorte Helenius, Thomas Werge, Andrew J. Schork, Andrés Ingason, LINC Consortium, George G. Kirov, Michael Owen, James Walters, Jane Lynch, David van Heel, Sarah Finer, Nicholas J Timpson, John MacLeod Verified, Julie Clayton, Ruby Tsang, Jane Sprackman, Shahid Khan, Inês Barroso, Rupert A Payne, Mark A. Mon-Williams, Megan Wood, Nabila Ali, Hilary C. Martin, Lam O. Huang, Marianne van den Bree, Ioanna K. Katzourou, Golam M. Khandakar
| JAMA Psychiatry Verified
Recurrent Copy Number Variants and Psychiatric Outcomes in the Context of Polygenic Scores Supplement 1. eFigure 1. Associated Odds Ratios and Confidence Intervals Resulted From the Sensitivity Analysis for Grouping rCNVs Across 6 Different Approaches eFigure 2. Comparison of rCNV Group-Associated Absolute Risk Between SSD and SSD Without Comorbid Childhood-Onset Disorders in iPSYCH2015 eFigure 3.
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Rethinking schizophrenia: insights from genomics and implications for research

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By Michael Owen, Michael O’Donovan
| Nature Verified
Abstract Recent genomic research, considered in the wider context of knowledge from outside genomics, provides significant conceptual insights into the aetiology and pathogenesis of schizophrenia. The evidence indicates that genetic risk is expressed across the lifespan, from foetal development through to adulthood, and involves multiple neuronal types and brain regions.
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Analysis of rare coding variants in schizophrenia-associated genes and generalised cognition in the UK Biobank

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By Eilidh Fenner, Peter A Holmans, Michael O’Donovan, Michael Owen, James Walters, Elliott Rees
| Nature Verified
Abstract Cognitive impairments in schizophrenia are associated with poor outcomes and are largely unimproved by current medications. It remains uncertain to what extent cognitive impairments arise from shared aetiology and biology with schizophrenia, or are a consequence of having the condition.
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