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Ruggero Barbieri

As seen in: BioRxiv
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Articles

Redirecting full-length FLT1 expression towards its soluble isoform promotes postischemic angiogenesis

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By Maja Bundalo, Sandra Vorlova, Jessica Ulrich, Ruggero Barbieri
| BioRxiv
Abstract Vascular endothelial growth factors and their tyrosine kinase receptors are key mediators of vasculogenesis and angiogenesis with FLT1 (VEGFR1) serving as a decoy receptor. A truncated mRNA transcript encoding soluble (s) FLT1 can be generated by premature cleavage and polyadenylation (APA).
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