Ruhit Sinha

Abstract Current in silico dialyser models remain accurate only under narrowly constrained conditions. Advances in computing power and increasing levels of interdisciplinary collaboration, however, now set the stage for more robust computational haemodialyser models.

Haemodialyser technology has not advanced much in decades, despite its unresolved shortcomings. Sophisticated new computational tools such as high-fidelity surrogate in silico dialyser models could reduce the time and expense of exploring alternative designs, dialysis dose and operating conditions compared with the current gold standard in vitro studies.