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Cancer-Associated Fibroblasts: Roles in Multidisciplinary Cancer Therapy and Targeted Strategies

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By Dehuan Zhang, Ruiang Cao
| preprints.org
This version is not peer-reviewed. Ruiang Cao,Dehuan Zhang  * Ruiang Cao,Dehuan Zhang  * You are already at the latest version Cancer-associated fibroblasts (CAFs) are one of the most abundant and critical cellular components in the tumor microenvironment (TME). They primarily originate from the activation of fibroblasts, and through complex interactions with tumor cells, immune cells, and extracellular matrix (ECM) components, ultimately promote tumor cell growth, migration, and invasion.
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