Ruihan Yan

1 Introduction The rapid expansion of nuclear energy and related technologies has intensified the global demand for efficient separation of radioactive isotopes (e.g., 235U, 239Pu, 147Pm, 90Sr) from complex waste streams, driven by both environmental safety imperatives and strategic resource recovery needs [1, 2].

β-amino sulfones are important motifs found in natural products and active pharmaceutical compounds. Herein, we report a general and highly regioselective intermolecular aminosulfonylation of alkenes via the homolysis of sulfinyl oximes from ketoximes and sulfinyl chloride. This method features catalyst-free, step-efficient functionalization and prominent functional group tolerance, providing a straightforward, green, and widely applicable approach to accessing β-amino sulfone derivatives.

β-amino sulfones are important motifs found in natural products and active pharmaceutical compounds. Herein, we report a general and highly regioselective intermolecular aminosulfonylation of alkenes via the homolysis of sulfinyl oximes from ketoximes and sulfinyl chloride. This method features catalyst-free, step-efficient functionalization and prominent functional group tolerance, providing a straightforward, green, and widely applicable approach to accessing β-amino sulfone derivatives.