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SERPINH1 derived from cancer-associated fibroblasts promotes epithelial-mesenchymal transition in clear cell renal cell carcinoma
Abstract Despite advances in cancer treatment, the prognosis of clear cell renal cell carcinoma (ccRCC) remains poor. The role of CAFs in ccRCC remains unclear. The single-cell sequencing (scRNA-seq) data for ccRCC were downloaded from the GEO database, with the SERPINH1+ fibroblast subpopulation identified. Cancer-associated fibroblasts (CAFs) were determined. In vitro assays analyzed SERPINH1 expression and its impact on ccRCC tumor progression.
Thermal Protection and Dielectric Properties of Borosilicate Coatings for SiCf/SiC Composites Under High-Temperature Oxidation
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Nomogram incorporating preoperative pan-immune-inflammation value and monocyte to high-density lipoprotein ratio for survival prediction in patients with colorectal cancer: a retrospective study | BMC Cancer | Full Text
References Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer statistics 2020: GLOBOCAN estimates of incidence and Mortality Worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209–49. Article PubMed Google Scholar Cervantes A, Adam R, Roselló S, Arnold D, Normanno N, Taïeb J, et al. Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Ann Oncol. 2023;34:10–32.
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