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Runali Sankhe on Muck Rack

Runali Sankhe

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Articles

Progression of glioblastoma downregulates neprilysin levels and enhances expression of oncogenic mediators in a rodent model

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By K. Pai, Dinesh Upadhya, Anoop Kishore, Runali Sankhe, Shivakumara K. Reddy, Adarsh Gopinathan, Farmiza Begum
| Nature Verified
Abstract In various cancers, tumor suppressor neprilysin plays a crucial role in preventing tumorigenesis. Neprilysin levels are decreased in various cancers and neuronal disorders. In the brain, NEP is expressed by astrocytes. However, the neprilysin levels with the oncogenic markers in glioblastoma has not been explored. In this study, we investigated the possible effects of glioblastoma progression on neprilysin signalling using a rat glioblastoma model.
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