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Articles by Ruolan Wang
Artikel "System-Scan"
Was hat sich hinter den Kulissen des Tanztheaters Wuppertal Pina Bausch abgespielt, bis Boris Charmatz das Haus verließ? Ein Beitrag von Ruolan Wang Ende Februar 2025 gaben das Tanztheater Wuppertal Pina Bausch und dessen Intendant Boris Charmatz eine überraschende Entscheidung bekannt: Die Zusammenarbeit solle zum Ende der Saison 2024/2025 vorzeitig beendet werden. Verblüffend, denn geplant war ein sehr viel längerfristiges Engagement.
Rational design of a Kappa opioid receptor peptide agonist with attenuated β-arrestin signaling
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Abstract Difelikefalin is an FDA-approved κ-opioid receptor (KOR) peptide agonist used to treat chronic pruritus. However, as a balanced agonist that activates both G protein and β-arrestin pathways, difelikefalin remains associated with undesirable side effects linked to β-arrestin signaling. Here, we report the cryo-EM structure of the difelikefalin-KOR-Gi complex, identifying Y3207.43 as a key residue that is critical for signaling bias.
By Huanhuan Zhang, Ruolan Wang, Pan Shi, Qingjun Zhu, Xinheng He, Youwei Xu, Qingning Yuan, Wen Hu, Kai Wu, Yong Zheng, Li Zhou Verified, Jun Liang, Pei Lv, Ziyan Xu, Fan Yang, Yingbin Liu, Youwen Zhuang, H. Xu, YUE WANG, Changlin Tian, Gaoming Wang
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Nature
Verified
Enhancing the targeting ability of metal–organic frameworks in cancer therapy and diagnosis
Abstract In cancer diagnosis and treatment, ‘accurate diagnosis’ and ‘targeted therapy’ are the primary focus and key goals of many research groups. Metal–organic frameworks (MOFs) have attracted considerable attention in cancer diagnosis and treatment owing to their structural diversity and multifunctionality. Starting in 2010, MOFs with targeting capabilities have been gradually developed and applied in the field of biomedicine.
Genome-Wide Identification and Expression Analysis of BrBASS Genes in Brassica rapa Reveals Their Potential Roles in Abiotic Stress Tolerance
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Machine Learning-Based Prediction of Stability in High-Entropy Nitride Ceramics
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Viruses | Free Full-Text | Dolutegravir + Lamivudine vs. Dolutegravir + Tenofovir Disoproxil Fumarate/Emtricitabine: Very-Low-Level HIV-1 Replication through 144 Weeks in the GEMINI-1 and GEMINI-2 Studies
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
A Comprehensive Literature Review of Treatment-Emergent Integrase Resistance with Dolutegravir-Based Regimens in Real-World Settings
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Genome-Wide Identification and Expression Analysis of BrGeBP Genes Reveal Their Potential Roles in Cold and Drought Stress Tolerance in Brassica rapa
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by †, †, , , , * and * College of Horticulture Science and Engineering, Shandong Agricultural University, Tai’an 271000, China * Authors to whom correspondence should be addressed. † These authors contributed equally to this work. Int. J. Mol. Sci.
Nitrogen Addition Affects Interannual Variation in Seed Production in a Tibetan Perennial Herb
1. Introduction The fundamental principle underlying life-history theory revolves around the notion of trade-offs and the allocation of scarce resources to either reproduction or growth and maintenance necessary for survival [1]. Furthermore, a considerable portion of perennial species demonstrates the ability to undergo multiple cycles of growth and reproduction, enabling them to reproduce across multiple seasons.
Assessing the Virologic Impact of Archived Resistance in the Dolutegravir/Lamivudine 2-Drug Regimen HIV-1 Switch Study TANGO through Week 144
Open AccessBrief Report by Ruolan Wang 1,*, Jonathan Wright 2, Parminder Saggu 2, Mounir Ait-Khaled 3, Riya Moodley 3, Chris M.
Relationships between the Mini-InDel Variants within the Goat CFAP43 Gene and Body Traits
Abstract : Simple Summary The cilia- and flagella-associated protein 43 (CFAP43) gene plays an important role in the formation of flagella and cilia, and limited research has been conducted on the effect of this gene on animal body traits. Herein, the relationships between three insertion/deletion polymorphisms (L-13, L-16, and L-19) of the goat CFAP43 gene and body traits were analyzed in 1827 Shaanbei white cashmere goats.
The Role of Tantalum Nanoparticles in Bone Regeneration Involves the BMP2/Smad4/Runx2 Signaling Pathway
Comments International Journal of Nanomedicine (2020) - doi: 10.2147/ijn.s245174 issn: 1178-2013 Guilan Zhang, Wenjing Liu, Ruolan Wang, Yanli Zhang, Liangjiao Chen, Aijie Chen, Haiyun Luo, Hui Zhong, Longquan Shao
On-chip single-mode high-Q terahertz whispering gallery mode resonator
Abstract The chip-scale terahertz (THz) devices and systems are helpful to enable actual applications in THz communication and sensing. Here, we demonstrate an on-chip THz whispering gallery mode resonator (WGMR) delivering a high-quality (Q) factor TE single mode, fabricated on a high-resistivity float zone silicon wafer by complementary metal–oxide–semiconductor compatible technology.
Mode coupling in a terahertz multi-mode whispering-gallery-mode resonator
Abstract We investigate mode-coupling effects of terahertz whispering-gallery modes (WGMs) in a multi-mode resonator using an extended transfer matrix method. Coupling effects between two WGMs are successfully observed on a well-designed high-Q terahertz Teflon ring resonator that supports low-order WGMs. The extended transmission matrix method is adopted to model, analyze, and reproduce terahertz single-band resonance and asymmetric dual-band resonances caused by mode coupling.
Potential adverse effects of nanoparticles on the reproductive system
Ruolan Wang,1 Bin Song,2 Junrong Wu,1 Yanli Zhang,1 Aijie Chen,1 Longquan Shao1,3 1Nanfang Hospital, Southern Medical University, Guangzhou 510515, China; 2Guizhou Provincial People’s Hospital, Guiyang 550002, China; 3Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, Guangzhou 510515, China Abstract: With the vigorous development of nanometer-sized materials, nanoproducts are becoming widely used in all aspects of life.
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