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Ruqiong Wang

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Articles

RBM10 Deficiency Promotes Anti-PD-1 Resistance in LUAD via STING Alternative Splicing-Driven CCL7 Signaling and Macrophage Polarization

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By Lishuang Qi, Weitong Gao, Ruqiong Wang
| Wiley Online Library Verified
1 Background Although chemotherapy and molecular-targeted therapy remain standard treatments for lung adenocarcinoma (LUAD), their clinical benefits are limited, prompting increasing interest in immunotherapeutic strategies [1, 2]. FDA-approved immune checkpoint inhibitors (ICIs) have achieved transformative success in LUAD, significantly improving objective response rates and overall survival (OS) [3, 4].
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