Rusudan Okujava on Muck Rack

Rusudan Okujava

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Articles

Pseudomonas aeruginosa breaches respiratory epithelia through goblet cell invasion in a microtissue model - Nature Microbiology

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By A. Leoni Swart, Pablo Manfredi, Rusudan Okujava
| Nature Verified
Abstract Pseudomonas aeruginosa, a leading cause of severe hospital-acquired pneumonia, causes infections with up to 50% mortality rates in mechanically ventilated patients. Despite some knowledge of virulence factors involved, it remains unclear how P. aeruginosa disseminates on mucosal surfaces and invades the tissue barrier. Using infection of human respiratory epithelium organoids, here we observed that P.
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