Ruth Pia Duecker on Muck Rack

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Articles

The ataxia-telangiectasia disease protein ATM controls vesicular protein secretion via CHGA and microtubule dynamics via CRMP5

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By Marina Reichlmeir, Jana Key, Ruth Pia Duecker, Hanna Roehrich
| biorxiv.org
Abstract The autosomal recessive disease ataxia-telangiectasia (A-T) presents with cerebellar degeneration, immunodeficiency, radiosensitivity, capillary dilatations, and pulmonary infections. Most symptoms outside the nervous system can be explained by failures of the disease protein ATM as Ser/Thr-kinase to coordinate DNA damage repair. However, ATM in adult neurons has cytoplasmic localization and vesicle association, where its roles remain unclear.
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Simple Measurement of IgA Predicts Immunity and Mortality in Ataxia-Telangiectasia

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By Stefan Zielen, Ruth Pia Duecker, Sandra Woelke, Helena Donath
| tu-dresden.de
Abstract Externe IDs PubMed 34477998 Schlagworte Ataxia-telangiectasia, IgA deficiency, Immunodeficiency, Immunoglobulins, Lymphopenia, Mortality
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