Rutie Yin
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Global research trends and hotspots in human immunodeficiency virus-associated cervical cancer (1990–2025): a multi-database bibliometric analysis
Abstract Background: Research on cervical cancer among WLWH represents a critical area for advancing long-term prevention and clinical management strategies. Yet as the volume of published literature in this field continues to grow rapidly, synthesizing and appraising the available evidence in a comprehensive manner has become increasingly challenging.
Cervical cancer with BRCA1 gene mutations: case reports and literature review
Abstract Background: Mutations in breast cancer susceptibility genes (BRCA1 and BRCA2) are well-established risk factors for breast, ovarian, prostate, and pancreatic cancers. However, their occurrence in cervical cancer is rare, with a reported prevalence of less than 5%. To date, only a limited number of cervical cancer cases harboring BRCA mutations have been reported. Case presentation: We conducted a retrospective analysis of two cases of cervical cancer with germline BRCA1 mutations.
Efficacy and safety of chiauranib in a combination therapy in platinum-resistant or refractory ovarian cancer: a multicenter, open-label, phase Ib and II study | Molecular Cancer | Full Text
From Jul 03, 2019, to Dec 21, 2020, a total of 46 patients were enrolled to receive chiauranib combination therapy (CE group: 24 patients; CP group: 22patients). In the pioneer phase Ib trial, 25 patients were enrolled to receive the monotherapy. In the monotherapy stage, the median patient age was 50 years (34 to 69 years), and 88% of patients had received three or more previous systemic therapies, with none classified as platinum-refractory ovarian cancer patients.
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