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Ruxia Hu on Muck Rack

Ruxia Hu

As seen in: Cell Reports Medicine
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Combined therapy with DR5-targeting antibody-drug conjugate and CDK inhibitors as a strategy for advanced colorectal cancer

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By Dongdong Zhou, Wenjun Wang, Jianming Huang, Jie Liu, Chao Zheng, Kai Zhang, Peng Xiong, Xin Chu, Weisong Li, Dongqin Liu, Xiangfu Zeng, Yong Zheng, Shuyong Zhang, Er’jiang Tang, Youban Xiao, Ruxia Hu, Feiqi Wang, Dexian Zheng, Liefeng Wang
| Cell Reports Medicine Verified
Keywords advanced colorectal cancer DR5 CDK4 antibody-drug conjugate Oba01 abemaciclib synergetic effect Introduction Colorectal cancer (CRC) is the third most common causes of cancer-related death and the second in terms of mortality, accounting for 10% of all cancer cases and related death.1,2 Among 20% of newly diagnosed patients with metastatic CRC, less than 20% survive for more than 5 years,3,4 making it a major public health and socioeconomic concern.
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