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Biocompatible Snowman-like Dimer Nanoparticles for Improved Cellular Uptake in Intrahepatic Cholangiocarcinoma
3. Results 3.1. Preparation and Characterization of PTX-Loaded PLA/Shellac Dimer NPs PLA, a type of polymeric material with excellent biocompatibility, biodegradability, and process ability [], and shellac, which is a biocompatible and biodegradable polymer that consists of polyesters and single esters, are both FDA-approved, as shown in []. PTX-loaded PLA/shellac dimer NPs (PLA/shellac-PTX dimer NPs) were prepared through rapid solvent exchange and controlled co-precipitation, as shown in a.
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