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Ryan N. Baugher on Muck Rack

Ryan N. Baugher

As seen in: Wiley Online Library, The Journal of Clinical Investigation
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Articles by Ryan N. Baugher

UGT1A1 Fragment Analysis: Genotyping the (TA) n Variable Repeat Polymorphism for Clinical Applications

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By Ryan N. Baugher, Kristen M. Pike, Teri M. Plona
| Wiley Online Library Verified
1 Background UGT1A1 is a gene involved in glucuronidation of many substances and plays a large role in the metabolism of drugs [1]. Variants within the gene are associated with reported variability in enzymatic activity; therefore, impacting pharmacokinetics and therapeutics, such as anticancer and antiretroviral agents [1, 2].
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Frameshift mutation spectra overlap between constitutional mismatch repair deficiency tumors and Lynch syndrome tumors

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By Yurong Song, Todd Young, Ryan N. Baugher, Brandon Somerville
| The Journal of Clinical Investigation
Research LetterIn-Press PreviewOncology Open Access | 10.1172/JCI185999 Frameshift mutation spectra overlap between constitutional mismatch repair deficiency tumors and Lynch syndrome tumors 1Vaccine, Immunity and Cancer Directorate, Frederick National Laboratory for Cancer Research, Frederick, United States of America 2Molecular Diagnostics Laboratory, Frederick National Laboratory for Cancer Research, Frederick, United States of America 3Clinical Research Directorate, Frederick National...
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