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S. Bares on Muck Rack

S. Bares

As seen in: British Pharmacological Society
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Articles

Inter‐ and intraindividual variability of long‐acting cabotegravir/rilpivirine pharmacokinetics after 1 year of continuous use

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By S. Sunagawa, J. R. Havens, S. Bares, M. Kubat
| British Pharmacological Society
16 Background: Low plasma concentrations of long-acting cabotegravir/rilpivirine (LA CAB/RPV) are associated with increased risk of virologic failure. However, real world data from the Swiss cohort found that trough LA CAB/RPV concentrations demonstrate high interindividual variability (coefficient of variation [CV]: CAB 31%, RPV 35%) and intraindividual variability (CV: CAB 52%, RPV 29%) during the first 12 months of use.
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