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S. Barichello on Muck Rack

S. Barichello

As seen in: Canadian Journal of Cardiology
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MASS SPETROMETRY EVIDENCE FOR THE MULTI-SITE PHOSPHORYLATION OF CARDIAC RYANODINE RECEPTOR 2 IN ATRIAL FIBRILLATION

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By S. Safabakhsh, R. Pancaroglu, D. S. Dissanayake, J. Parker, S. Barichello, P. Panwar, P. C. Hanson, G. Singhera, F. Van Petegem, Z. W. Laksman
| Canadian Journal of Cardiology Verified
Atrial fibrillation (AF) is the most common sustained arrhythmia. Currently, there are no biomarkers available for monitoring AF progression or for serving as targets for disease-modifying therapies. Research in this area is increasingly pointing to a role for post-translational phosphorylation of cardiac ryanodine receptor 2 (RyR2) as a promising avenue for biomarker discovery. Most studies of RyR2 phosphorylation in AF have focused on single phosphorylation sites using antibody-based assays.
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