S. Chakra Chennubhotla on Muck Rack

S. Chakra Chennubhotla

As seen in: Nature
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Articles

Spatial domain analysis predicts risk of colorectal cancer recurrence and infers associated tumor microenvironment networks

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By Shikhar Uttam, Albert Gough, S. Chakra Chennubhotla
| Nature
Abstract An unmet clinical need in solid tumor cancers is the ability to harness the intrinsic spatial information in primary tumors that can be exploited to optimize prognostics, diagnostics and therapeutic strategies for precision medicine. Here, we develop a transformational spatial analytics computational and systems biology platform (SpAn) that predicts clinical outcomes and captures emergent spatial biology that can potentially inform therapeutic strategies.
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