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Living cells continually interact with their extracellular matrix (ECM) through cell surface receptors and ligands, facilitating diverse cellular behaviors, such as proliferation, migration, differentiation, and apoptosis [1], [2], [3]. Integrins, for instance, bind to cell-adhesive moieties, such as the Arg-Gly-Asp (RGD) tripeptide sequences present in fibronectin, vitronectin, and collagen [4], [5], [6].
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