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Saai Suryanarayanan on Muck Rack

Saai Suryanarayanan

As seen in: BioRxiv
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Articles

Sperm activation for fertilization requires robust activity of the TAT-5 lipid flippase

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By Katherine A. Maniates, Saai Suryanarayanan, Alissa Rumin, Morgan Lewin
| BioRxiv
Abstract During fertilization, sperm and egg membranes signal and fuse to form a zygote and begin embryonic development. Here, we investigated the role of lipid asymmetry in gametogenesis, fertilization, and embryogenesis. We find that phosphatidylethanolamine asymmetry is lost during meiosis prior to phosphatidylserine exposure.
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The Caenorhabditis elegans spe-21 gene that encodes a palmitoyltransferase is necessary for spermiogenesis.

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By Dawn Chen, Yamei Zuo, Elizabeth Gleason, Saai Suryanarayanan
| BioRxiv
Abstract In most animals, spermatids that are produced must further differentiate into fertilization-competent spermatozoa after completing meiosis. In Caenorhabditis elegans, this process is known as spermiogenesis or spermatid activation and it results in the transformation of round, non-motile spermatids into amoeboid, motile spermatozoa. Spermatid activation in C.
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