Sabine Schulz

Abstract Foam cells in atheroma are engorged with lipid droplets (LDs) that contain esters of regulatory lipids whose metabolism remains poorly understood. LD-associated hydrolase (LDAH) has a lipase structure and high affinity for LDs of foam cells. Using knockout and transgenic mice of both sexes, here we show that LDAH inhibits atherosclerosis development and promotes stable lesion architectures.

Monday, 29 July 2024, 12:24 El Rompido might be on the coast but, paradoxically, it takes a boat trip to reach the sea. This is because of a long sand bank - La Flecha (the arrow) - that runs parallel to the coastline in this part of the province of Huelva in western Andalucía. For the locals, this has the advantage that they are protected from the forces of the sea, as the mouth of the river Piedras and the strip of sand lie between them.

This is an early access version, the complete PDF, HTML, and XML versions will be available soon.