Sadashiva Karnik on Muck Rack

Sadashiva Karnik

As seen in: Nature, ACS Publications
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Articles

Structural Insights into Recognition and Translocation of Oxidized Phospholipid by CD36 Using Mass Spectrometry, Molecular Docking, Dynamics, and Metadynamics Simulations

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By Tatiana Byzova, Detao Gao, Khuraijam Dhanachandra Singh, Sadashiva Karnik
| dx.doi.org
Introduction Click to copy section linkSection link copied! CD36 is a multifunctional receptor widely expressed in immune cells such as macrophages, dendritic cells, platelets, T cells, and B cells, as well as in nonimmune cells including myocytes, adipocytes, microvascular endothelial cells, and specialized epithelial cells.
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Structural Insights into Recognition and Translocation of Oxidized Phospholipid by CD36 Using Mass Spectrometry, Molecular Docking, Dynamics, and Metadynamics Simulations

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By Tatiana Byzova, Detao Gao, Khuraijam Dhanachandra Singh, Sadashiva Karnik
| ACS Publications
Introduction Click to copy section linkSection link copied! CD36 is a multifunctional receptor widely expressed in immune cells such as macrophages, dendritic cells, platelets, T cells, and B cells, as well as in nonimmune cells including myocytes, adipocytes, microvascular endothelial cells, and specialized epithelial cells.
Open in Who Shared Issue with article?

Gut microbe-generated phenylacetylglutamine is an endogenous allosteric modulator of β2-adrenergic receptors - Nature Communications

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By James Anderson, Deepthi P. Mallela, Niladri S. Kar, Terri J. Harford, Michael Fischbach, J. Brown, Sadashiva Karnik, Joseph A. DiDonato, Maradumane L. Mohan
| Nature Verified
Abstract Allosteric modulation is a central mechanism for metabolic regulation but has yet to be described for a gut microbiota-host interaction. Phenylacetylglutamine (PAGln), a gut microbiota-derived metabolite, has previously been clinically associated with and mechanistically linked to cardiovascular disease (CVD) and heart failure (HF).
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