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Sadra Habibi Moini

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Articles

Osteopontin in Alzheimer's Disease: A Double‐Edged Sword in Neurodegeneration and Neuroprotection-A Systematic Review

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By Zahra Azizan, Maryam Bazrgar, Narges Bazgir, Sadra Habibi Moini
| Wiley Online Library Verified
1 Introduction Alzheimer's disease (AD), the most prevalent form of dementia worldwide [1], is a progressive neurodegenerative disorder characterized by the aggregation of amyloid-beta (Aβ) plaques and hyperphosphorylated tau protein in neurofibrillary tangles (NFTs) within the brain parenchyma [2]. Despite significant research efforts, the intricate mechanisms underlying AD pathogenesis remain largely unresolved.
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