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Saeed Reza Pakzad on Muck Rack

Saeed Reza Pakzad

As seen in: Nature
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Articles

Impact of Leishmania RNA virus 2 on immune response and pathogenesis in Leishmania major -infected BALB/c mice

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By Asal Katebi, Soheila Ajdary, Farhad Riazi-rad, Saeed Reza Pakzad
| Nature Verified
Abstract Leishmania RNA virus (LRV)1 has been associated with altered disease outcomes in cutaneous leishmaniasis (CL), but the role of LRV2 in Leishmania major (L. major) infection remains poorly understood. This study investigated the impact of LRV2-positive L. major (Lm-LRV2+) on disease progression and host immune responses. J774A.1 macrophages were infected with Lm-LRV2+ or LRV2- (Lm-LRV2-) parasites, and cytokine gene expression was measured by qPCR.
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