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Saili Chabukswar on Muck Rack

Saili Chabukswar

As seen in: Wiley Online Library, MDPI
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Articles

HERV Modulation in Colorectal Carcinoma Patients: A Snapshot of Endogenous Retroviral Transcriptome

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By Nicole Grandi, Ching-Hsuan Liu, Saili Chabukswar, Daniele Carta
| Wiley Online Library Verified
1 Introduction Colorectal cancer (CRC) is the third most diagnosed cancer as well as the second-highest cause of cancer-related deaths globally, with a 15% of 5-year survival rate for the metastatic form. The etiology of CRC is still unclear, and great attention is dedicated to the possible impact of microbial agents on its onset and progression.
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Envelope Recombination: A Major Driver in Shaping Retroviral Diversification and Evolution within the Host Genome

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By Nicole Grandi, Liang-Tzung Lin, Enzo Tramontano, Saili Chabukswar
| MDPI
1. Introduction Retroviridae is a widely distributed family of RNA viruses that follows a replication cycle involving the reverse transcription of viral single-stranded RNA (ssRNA) into double-stranded DNA (dsDNA), which is inserted into the genome of host cells, thus enabling the expression of viral genes. Usually, retroviruses infect somatic cells but the possibility of infecting germ line cells provides a means for the colonization and fixation of retroviruses into the host genome.
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