Sajad Ataei Azimi

1 Introduction Eosinophilic fasciitis (EF), also known as Shulman's syndrome, is a rare connective tissue disorder characterized by inflammation and thickening of the fascia. This condition is often associated with peripheral eosinophilia, and its exact cause remains unknown. Symptoms of EF primarily include skin hardening and stiffness, particularly in the extremities [1, 2]. Standard treatment typically consists of high-dose corticosteroids and immunosuppressive agents, such as methotrexate.