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Mutational analysis of multidrug efflux pump (AcrAB-TolC) in E nterobacter cloacae isolates from clinical samples
Abstract In Gram-negative bacterial pathogens, multidrug efflux pump’s role is being studied as one of the critical mechanisms to develop antibiotics resistance. The current study was designed to characterize the AcrAB-TolC efflux pump genes to determine its role in multidrug resistance of hospital-acquired Enterobacter cloacae. In this cross-sectional descriptive study, a total of 200 clinical samples were collected for the isolation of E.
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