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Sakshar Chakravarty on Muck Rack

Sakshar Chakravarty

As seen in: Nature, BioRxiv, Genome Research
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Articles

RAmbler resolves complex repeats in human Chromosomes 8, 19, and X

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By Sakshar Chakravarty, Glennis A. Logsdon, Stefano Lonardi
| Genome Research
1,3 1 University of California, Riverside; 2 University of Pennsylvania ↵* Corresponding author; email: stelo{at}cs.ucr.edu Received March 13, 2024. Accepted February 6, 2025. This manuscript is Open Access. This article, published in Genome Research, is available under a Creative Commons License (Attribution-NonCommercial 4.0 International license), as described at http://creativecommons.org/licenses/by-nc/4.0/.
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RAmbler: de novo genome assembly of complex repetitive regions

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By Sakshar Chakravarty, Glennis A. Logsdon, Stefano Lonardi
| BioRxiv
Abstract Complex repetitive regions (also called segmental duplications) in eukaryotic genomes often contain essential functional and regulatory information. Despite remarkable algorithmic progress in genome assembly in the last twenty years, modern de novo assemblers still struggle to accurately reconstruct these highly repetitive regions. When sequenced reads will be long enough to span all repetitive regions, the problem will be solved trivially.
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RAmbler: de novo genome assembly of complex repetitive regions

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By Sakshar Chakravarty, Glennis A. Logsdon, Stefano Lonardi
| BioRxiv
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