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Salvo Danilo Lombardo on Muck Rack

Salvo Danilo Lombardo

As seen in: Science Magazine, BioRxiv
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Articles

A multilayer network approach elucidates time- and tissue-specific developmental and aging processes

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By Salvo Danilo Lombardo, André Figueiredo Rendeiro, Jörg Menche
| BioRxiv
Abstract Understanding the dynamic interplay of proteins across different life stages and tissues is essential for deciphering the molecular mechanisms underpinning development, aging, and disease. Here, we present a comprehensive network-based framework that constructs and integrates 119 time- and tissue-specific protein-protein interaction (PPI) networks derived from transcriptomic data, offering insights into proteomic dynamics across the human lifespan.
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