Sam Barnett

Abstract Aging governs human lifespan and health span through cellular and molecular mechanisms that are incompletely understood. Over time, aging leads to decline in physiological function and increased vulnerability to disease. A crucial question is whether aging mechanisms can be therapeutically modulated before functional decline begins. A key challenge, however, is understanding these mechanisms to the resolution of individual cells across different organs.

Med J Aust || doi: 10.5694/mja2.52671 Published online: 26 May 2025 Globally, respiratory syncytial virus (RSV) is responsible for an estimated 33 million acute lower respiratory tract infections, resulting in 26 300 in‐hospital deaths annually in children aged 0 to 60 months.1 Children under the age of 4 years are disproportionately impacted and represent 50% of cases, with infants under the age of 6 months accounting for most of the RSV‐associated hospitalisations in Australia.2 The...

Correction to: Nature https://doi.org/10.1038/s41586-023-06311-1 Published online 12 July 2023 In the drug2cell analysis of the initially published article, there was an error in filtering drug and target interactions. The activity (pChEMBL) threshold for these interactions was specifically set for each family of target molecules in accordance with the Illuminating the Druggable Genome (IDG) project. In the original manuscript, there was a discrepancy with the values from the IDG project1.