Samadhi Kulasooriya on Muck Rack

Samadhi Kulasooriya

As seen in: eLife
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Articles

The dual molecular identity of vestibular kinocilia bridges structural and functional traits of primary and motile cilia

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By Amirrasoul Tavakoli, Samadhi Kulasooriya, Zhanhong Xu
| eLife
eLife Assessment Using single-cell transcriptomic data from mouse inner ear hair cells, the authors compare for the first time gene expression across the four recognized hair cell types in adults, generating information fundamental to understanding hair cell relationships between the ancient vestibular compartment and the more recent cochlea.
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Single-cell Transcriptomics Unravel Stereocilia Degeneration as a Key Contributor to Age-related Vestibular Dysfunction in Mice and Humans

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By Huizhan Liu, Sarath Vijayakumar, Samadhi Kulasooriya, Celia Bloom
| biorxiv.org
Abstract Age-related vestibular dysfunction (ARVD) is a prevalent, debilitating condition in the elderly. The etiology and molecular mechanisms are poorly understood. We focused on mechanosensitive hair cells (HCs) as they are particularly vulnerable to aging.
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