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Samaksh Singh on Muck Rack

Samaksh Singh

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Articles

Bulk delivery of a preassembled apical surface initiates epithelial lumen formation

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By Sujasha Ghosh, Eleanor Martin, Yuhong Chen, Rossana Girardello, Gunnar Dittmar, Alexander Ludwig, Natasha Amiera, Samaksh Singh, Barbara Hübner
| Nature Verified
Abstract During de novo lumenogenesis, epithelial cells establish luminal identity by directing apical cargo to an apical membrane initiation site (AMIS). Although this process has been widely studied, the mechanisms governing AMIS formation and its progression into a luminal precursor remain poorly understood.
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