Samavath Mallawarachchi

Introduction Click to copy section linkSection link copied! Detecting and targeting cancer biomarkers is a key research focus in modern oncology. (1) This study presents a novel in silico technique to design peptide binders targeting prominin-1 and sortilin, two medically significant biomarkers.

Abstract Candidatus Liberibacter asiaticus (CLas) is a phloem-limited bacterium that causes the citrus greening disease. One of the main challenges in treating citrus greening disease is delivering the therapeutic agents to the vascular system where CLas bacteria reside. This study proposes Polydiallyldimethylammonium chloride (poly(DADMAC)) incorporated lipid nanoparticles as a potential method to deliver the drugs into the plant vascular system via foliar application.

Abstract Electronic nicotine delivery systems have recently achieved great popularity as safer alternatives to traditional tobacco. However, there is growing evidence that vaping is not harmless, with documented acute and chronic health effects. This study investigated how components of vape juice interact with human Angiotensin-converting enzyme 2 (ACE2) receptors, using molecular docking, molecular dynamics simulations, and Biolayer Interferometry (BLI).