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Samuel Benjamin Perkowski on Muck Rack

Samuel Benjamin Perkowski

As seen in: BioRxiv
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Articles

Shh signaling directs dorsal ventral patterning in the regenerating X. tropicalis spinal cord

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By Avery Angell Swearer, Samuel Benjamin Perkowski, Andrea Elizabeth Wills
| BioRxiv
Abstract Tissue development and regeneration rely on the deployment of embryonic signals to drive progenitor activity and thus generate complex cell diversity and organization. One such signal is Sonic Hedgehog (Shh), which establishes the dorsal-ventral (D/V) axis of the spinal cord during embryogenesis. However, the existence of this D/V axis and its dependence on Shh signaling during regeneration varies by species.
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