Samuel Milton

Nitrogen-fused polycyclic indoles, such as dihydropyrido[1,2-a]-indolones (DHPIs), are widespread structural motifs in natural products and pharmaceutical compounds, many of which display notable pharmacological properties and biological activities (Figure 1). (1) Consequently, substantial efforts have been devoted to their construction by both synthetic and medicinal chemists, leading to the development of numerous elegant methods.

Nitrogen-fused polycyclic indoles, such as dihydropyrido[1,2-a]-indolones (DHPIs), are widespread structural motifs in natural products and pharmaceutical compounds, many of which display notable pharmacological properties and biological activities (Figure 1). (1) Consequently, substantial efforts have been devoted to their construction by both synthetic and medicinal chemists, leading to the development of numerous elegant methods.

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