Samuel Owen Purvine on Muck Rack

Samuel Owen Purvine

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Articles

Structural reorganization of the fungal endoplasmic reticulum upon induction of mycotoxin biosynthesis

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By Scott Baker, Samuel Owen Purvine, William Byron Chrisler, Carrie Diana Nicora
| Nature Verified
Structural changes of the ER in F. graminearum were studied using reporter strains expressing fluorescence tagged proteins (Table 1). Schemes detailing tagging strategies and validations for transformants are provided (Supplementary Fig. S1; primer sequences in Supplementary Table S1). Hmr1 is a key enzyme in the isoprenoid biosynthetic pathway, catalyzing the rate limiting step in the synthesis of farnesyl pyrophosphate, the initial substrate for TRI biosynthesis (Fig. 1).
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